Document 0157
 DOCN  M9480157
 TI    Automat: a novel software system for the systematic search for protein
       (or DNA) similarities with a notable application to autoimmune diseases
       and AIDS.
 DT    9410
 AU    Cantalloube H; Nahum C; Achour A; Lehner T; Callebaut I; Burny A;
       Bizzini B; Mornon JP; Zagury D; Zagury JF; Universite P. et M. Curie,
       Paris, France.
 SO    Comput Appl Biosci. 1994 Apr;10(2):153-61. Unique Identifier : AIDSLINE
       MED/94290911
 AB    Automat is a novel program which finds exhaustively all the oligopeptide
       segments shared by a given protein of any size with the proteins of a
       whole databank. It allows the user to collect statistics on the
       composition of the sequence studied in reference to the databank used.
       We present here the rationale and the algorithm underlying this powerful
       software. Besides its immediate interest for identifying efficiently
       similarities between proteins (or DNAs), biological applications of this
       software have already been described in the case of HIV-1 viral
       proteins, and Automat should prove useful also for studying more
       generally autoimmune diseases.
 DE    Acquired Immunodeficiency Syndrome/*GENETICS  Algorithms  Amino Acid
       Sequence  Autoimmune Diseases/*GENETICS  Human  HIV/*CHEMISTRY
       Molecular Sequence Data  *Sequence Alignment  Sequence Analysis, DNA
       *Software  Support, Non-U.S. Gov't  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).